diffHic: a Bioconductor package to detect differential genomic interactions in Hi-C data

Abstract

Chromatin conformation capture with high-throughput sequencing (Hi-C) is a technique that measures the in vivo intensity of interactions between all pairs of loci in the genome. Most conventional analyses of Hi-C data focus on the detection of statistically significant interactions. However, an alternative strategy involves identifying significant changes… (More)
DOI: 10.1186/s12859-015-0683-0

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Cite this paper

@inproceedings{Lun2015diffHicAB, title={diffHic: a Bioconductor package to detect differential genomic interactions in Hi-C data}, author={Aaron T. L. Lun and Gordon K. Smyth}, booktitle={BMC Bioinformatics}, year={2015} }