des-AA-1,2,5[D-Trp8, IAmp9]somatostatin-14 allows the identification of native rat somatostatin sst1 receptor subtype.

@article{Leroux1997desAA125DTrp8IA,
  title={des-AA-1,2,5[D-Trp8, IAmp9]somatostatin-14 allows the identification of native rat somatostatin sst1 receptor subtype.},
  author={Philippe Leroux and Christine Bucharles and Erwin Bologna and Hubert Vaudry},
  journal={European journal of pharmacology},
  year={1997},
  volume={337 2-3},
  pages={333-6}
}
Somatostatin exerts multiple activities by interacting with at least five different receptor subtypes (sst[1-5]). The affinity of des-AA(1,2,5)-[D-Trp8, IAmp9]somatostatin-14 (CH-275) was studied by competition experiments using the non-selective radioligand [125I][Leu8, D-Trp22, Tyr25]somatostatin-28 in areas of the rat brain and pituitary known to express… CONTINUE READING