dbCoRC: a database of core transcriptional regulatory circuitries modeled by H3K27ac ChIP-seq signals

Abstract

Core transcription regulatory circuitry (CRC) is comprised of a small group of self-regulated transcription factors (TFs) and their interconnected regulatory loops. Studies from embryonic stem cells and other cellular models have revealed the elementary roles of CRCs in transcriptional control of cell identity and cellular fate. Systematic identification… (More)
DOI: 10.1093/nar/gkx796

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