d-cycloserine reverses the detrimental effects of stress on learning in females and enhances retention in males.

@article{Waddell2010dcycloserineRT,
  title={d-cycloserine reverses the detrimental effects of stress on learning in females and enhances retention in males.},
  author={Jaylyn Waddell and Elyse M. Mallimo and Tracey J. Shors},
  journal={Neurobiology of learning and memory},
  year={2010},
  volume={93 1},
  pages={31-6}
}
Exposure to acute, inescapable stress produces a facilitation of subsequent classical eyeblink conditioning in male rats. The same stress exposure produces a profound deficit in classical eyeblink conditioning in females. Activation of N-methyl-d-aspartate receptors (NMDAr) is necessary for the effect of stress on learning in males while the contribution of NMDAr activation to the deficit in learning after stress is unknown. Here, we tested the influence of d-cycloserine (DCS), a positive… CONTINUE READING
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