colgate/hdac1 Repression of foxd3 expression is required to permit mitfa-dependent melanogenesis.

@article{Ignatius2008colgatehdac1RO,
  title={colgate/hdac1 Repression of foxd3 expression is required to permit mitfa-dependent melanogenesis.},
  author={Myron S. Ignatius and Holly E Moose and Heithem M. El-Hodiri and Paul D. Henion},
  journal={Developmental biology},
  year={2008},
  volume={313 2},
  pages={568-83}
}
Neural crest-derived pigment cell development has been used extensively to study cell fate specification, migration, proliferation, survival and differentiation. Many of the genes and regulatory mechanisms required for pigment cell development are conserved across vertebrates. The zebrafish mutant colgate (col)/histone deacetylase1 (hdac1) has reduced numbers, delayed differentiation and decreased migration of neural crest-derived melanophores and their precursors. In hdac1(col) mutants normal… CONTINUE READING

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