circ-SHKBP1 Regulates the Angiogenesis of U87 Glioma-Exposed Endothelial Cells through miR-544a/FOXP1 and miR-379/FOXP2 Pathways

@inproceedings{He2018circSHKBP1RT,
  title={circ-SHKBP1 Regulates the Angiogenesis of U87 Glioma-Exposed Endothelial Cells through miR-544a/FOXP1 and miR-379/FOXP2 Pathways},
  author={Qianru He and Lini Zhao and Yunhui Liu and Xiaobai Liu and Jian Zheng and Hai Yu and Heng Cai and Jun Ma and Libo Liu and Ping Wang and Zhen Li and Yi-xue Xue},
  booktitle={Molecular therapy. Nucleic acids},
  year={2018}
}
Circular RNAs (circRNAs) are a type of endogenous non-coding RNAs, which have been considered to mediate diverse tumorigenesis including angiogenesis. The present study aims to elucidate the potential role and molecular mechanism of circ-SHKBP1 in regulating the angiogenesis of U87 glioma-exposed endothelial cells (GECs). The expression of circ-SHKBP1, but not linear SHKBP1, was significantly upregulated in GECs compared with astrocyte-exposed endothelial cells (AECs). circ-SHKBP1 knockdown… CONTINUE READING
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