chainCleaner improves genome alignment specificity and sensitivity


Motivation Accurate alignments between entire genomes are crucial for comparative genomics. However, computing sensitive and accurate genome alignments is a challenging problem, complicated by genomic rearrangements. Results Here we present a fast approach, called chainCleaner, that improves the specificity in genome alignments by accurately detecting and… (More)
DOI: 10.1093/bioinformatics/btx024


7 Figures and Tables

Slides referencing similar topics