chainCleaner improves genome alignment specificity and sensitivity

Abstract

Motivation Accurate alignments between entire genomes are crucial for comparative genomics. However, computing sensitive and accurate genome alignments is a challenging problem, complicated by genomic rearrangements. Results Here we present a fast approach, called chainCleaner, that improves the specificity in genome alignments by accurately detecting and… (More)
DOI: 10.1093/bioinformatics/btx024

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