ccrA1: a mutation in Streptomyces coelicolor that affects the control of catabolite repression.

The regulation of carbon utilization is of central importance in the gene expression pathways for both morphological development and antibiotic production in Streptomyces species. We report the identification and characterization of a mutation in Streptomyces coelicolor, ccrA1, that affects the expression of several catabolite-controlled promoters. ccrA1… CONTINUE READING