cPKC-dependent sequestration of membrane-recycling components in a subset of recycling endosomes.

@article{Becker2003cPKCdependentSO,
  title={cPKC-dependent sequestration of membrane-recycling components in a subset of recycling endosomes.},
  author={Kevin P Becker and Yusuf A. Hannun},
  journal={The Journal of biological chemistry},
  year={2003},
  volume={278 52},
  pages={52747-54}
}
In addition to the classical role of protein kinase C (PKC) as a mediator of transmembrane signals initiated at the plasma membrane, there is also significant evidence to suggest that a more sustained PKC activity is necessary for a variety of long term cellular responses. To date, the subcellular localization of PKC during sustained activation has not been extensively studied. We report here that long term activation of PKC (1 h) leads to the selective translocation of classical PKC isoenzymes… CONTINUE READING

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