cGMP-gated conductance in retinal bipolar cells is suppressed by the photoreceptor transmitter.

@article{Nawy1991cGMPgatedCI,
  title={cGMP-gated conductance in retinal bipolar cells is suppressed by the photoreceptor transmitter.},
  author={Scott Nawy and Craig E. Jahr},
  journal={Neuron},
  year={1991},
  volume={7 4},
  pages={677-83}
}
Transmitter release from photoreceptors is decreased by light, resulting in a conductance increase in depolarizing bipolar cells. Addition of exogenous cGMP through a patch pipette to depolarizing bipolar cells from slices of dark-adapted tiger salamander retina resulted in an enhancement of the light response. This enhancement was blocked by GTP-gamma-S… CONTINUE READING