cGMP-dependent protein kinase Iβ phosphorylates and regulates the function of the actin/myosin-associated protein caldesmon

Abstract

Background The type I cGMP-dependent protein kinases (PKGIa and PKGIb) are splice variants that differ in their first ~100 amino acids, giving each isoform unique dimerization and autoinhibitory domains. The unique coiled-coil dimerization domains mediate isoform specific proteinprotein interactions, and we have previously identified the amino acids that… (More)
DOI: 10.1186/2050-6511-14-S1-P13

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