cGMP antagonizes angiotensin-mediated phosphatidylcholine hydrolysis and C kinase activation in mesangial cells.

@article{Barnett1995cGMPAA,
  title={cGMP antagonizes angiotensin-mediated phosphatidylcholine hydrolysis and C kinase activation in mesangial cells.},
  author={Ronald L. Barnett and Lynda Ruffini and Leslie S. Ramsammy and Rosemarie Pasmantier and Michael M. Friedlaender and Edward P. Nord},
  journal={The American journal of physiology},
  year={1995},
  volume={268 2 Pt 1},
  pages={C376-81}
}
Previous studies from this laboratory have shown that in cultured rat mesangial cells (MC), angiotensin II (ANG II) mediates its effects via activation of phosphatidylinositol-specific phospholipase C (PI-PLC) and phosphatidylcholine-specific phospholipase C (PC-PLC) and phospholipase D (PC-PLD). In addition, guanosine 3',5'-cyclic monophosphate (cGMP… CONTINUE READING