cDNA sequence and genomic characterization of intracisternal A-particle-related retroviral elements containing an envelope gene.

@article{Reuss1991cDNASA,
  title={cDNA sequence and genomic characterization of intracisternal A-particle-related retroviral elements containing an envelope gene.},
  author={Frank U. Reuss and H. Chica Schaller},
  journal={Journal of virology},
  year={1991},
  volume={65 11},
  pages={5702-9}
}
Intracisternal A-particle retrotransposons (IAPs) are retroviruslike elements that are defective in envelope protein synthesis and exist without an extracellular stage. We have isolated a novel class of cDNAs that are related to known IAP elements in the nucleotide and deduced protein sequence of gag and pol genes but also contain a previously unidentified reading frame between the pol gene and putative U3 region. Analysis of the deduced protein sequence reveals features of the putative protein… CONTINUE READING

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Pushing the endogenous envelope

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