cDNA expression array analysis of gene expression in human hepatocarcinoma Hep3B cells induced by BNIPL-1.

@article{Xie2005cDNAEA,
  title={cDNA expression array analysis of gene expression in human hepatocarcinoma Hep3B cells induced by BNIPL-1.},
  author={Li Xie and Wen-Xin Qin and Jin-jun Li and Xianghuo He and H D Shu and Gen-Fu Yao and Da-fang Wan and Jian-ren Gu},
  journal={Acta biochimica et biophysica Sinica},
  year={2005},
  volume={37 9},
  pages={618-24}
}
Bcl-2/adenovirus E1B 19 kDa interacting protein 2 like-1 (BNIPL-1) is a novel human protein identified in our laboratory, which can interact with Bcl-2 and Cdc42GAP and induce apoptosis via the BNIP-2 and Cdc42GAP homology (BCH) domain. In the present study, we established the Hep3B-Tet-on stable cell line in which expression of BNIPL-1 can be induced by doxycycline. The cell proliferation activity assay showed that the overexpression of BNIPL-1 suppresses Hep3B cell growth in vitro. The… CONTINUE READING

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