cDNA cloning demonstrates the expression of pregnancy-specific glycoprotein genes, a subgroup of the carcinoembryonic antigen gene family, in fetal liver.

@article{Zimmermann1989cDNACD,
  title={cDNA cloning demonstrates the expression of pregnancy-specific glycoprotein genes, a subgroup of the carcinoembryonic antigen gene family, in fetal liver.},
  author={W. Zimmermann and M. Weiss and J. Thompson},
  journal={Biochemical and biophysical research communications},
  year={1989},
  volume={163 3},
  pages={
          1197-209
        }
}
  • W. Zimmermann, M. Weiss, J. Thompson
  • Published 1989
  • Biology, Medicine
  • Biochemical and biophysical research communications
  • The pregnancy-specific glycoprotein (PSG) genes constitute a subgroup of the carcinoembryonic antigen (CEA) gene family. Here we report the cloning of four cDNAs coding for different members of the PSG family from a human fetal liver cDNA library. They are derived from three closely related genes (PSG1, PSG4 and PSG6). Two of the cDNA clones represent splice variants of PSG1 (PSG1a, PSG1d) differing in their C-terminal domain and 3'-untranslated regions. All encoded proteins show the same… CONTINUE READING
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    Figures, Tables, and Topics from this paper

    The human pregnancy-specific glycoprotein genes are tightly linked on the long arm of chromosome 19 and are coordinately expressed.
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