cDNA cloning and deduced amino acid sequence of fibrinolytic enzyme (lebetase) from Vipera lebetina snake venom.

@article{Siigur1996cDNACA,
  title={cDNA cloning and deduced amino acid sequence of fibrinolytic enzyme (lebetase) from Vipera lebetina snake venom.},
  author={Ene Siigur and Anu Aasp{\~o}llu and Anthony T. Tu and J{\"u}ri Siigur},
  journal={Biochemical and biophysical research communications},
  year={1996},
  volume={224 1},
  pages={229-36}
}
The complete amino acid sequence of lebetase is deduced from the nucleotide sequence of a cDNA clone isolated by screening a venomous gland c DNA library of Central Asian Vipera lebetina snake. The cDNA sequence with 2011 basepairs encodes an open reading frame of 478 amino acids which includes an 18 amino acid signal peptide, plus an 175 amino acid segment of zymogen-like propeptide, a mature protein of 204 amino acids, a spacer of 18 amino acids and a disintegrin-like peptide of 63 amino… CONTINUE READING

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