cDNA and gene analyses imply a novel structure for a rat carcinoembryonic antigen-related protein.

@article{Rebstock1990cDNAAG,
  title={cDNA and gene analyses imply a novel structure for a rat carcinoembryonic antigen-related protein.},
  author={Sabine Rebstock and K. Lucas and John A. Thompson and Wolfgang Zimmermann},
  journal={The Journal of biological chemistry},
  year={1990},
  volume={265 14},
  pages={7872-9}
}
The gene encoding the human tumor marker carcinoembryonic antigen (CEA) belongs to a gene family which can be subdivided into the CEA and the pregnancy-specific glycoprotein subgroups. The corresponding proteins are members of the immunoglobulin superfamily, characterized through the presence of one IgV-like domain and a varying number of IgC-like domains. Since the function of the CEA family is not well understood, we decided to establish an animal model in the rat to study its tissue-specific… CONTINUE READING