cAMP signalling is involved in growth, germination, mycoparasitism and secondary metabolism in Trichoderma virens.

@article{Mukherjee2007cAMPSI,
  title={cAMP signalling is involved in growth, germination, mycoparasitism and secondary metabolism in Trichoderma virens.},
  author={Mala Mukherjee and Prasun Kumar Mukherjee and Sharad P. Kale},
  journal={Microbiology},
  year={2007},
  volume={153 Pt 6},
  pages={1734-42}
}
An adenylate-cyclase-encoding gene, tac1, of Trichoderma virens, a soil fungus used in the biocontrol of plant pathogens, has been cloned and sequenced. The tac1 ORF spanned 7032 bp, encoding a protein of 2153 aa, which shared an identity of 65 % with the adenylate cyclase of Colletotrichum lagenarium. Deletion of tac1, through double-crossover homologous recombination, lowered the intracellular cAMP levels to below the detection limit. The mutants showed only 5-6 % of the wild-type growth rate… CONTINUE READING

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