cAMP receptor protein-cAMP plays a crucial role in glucose-lactose diauxie by activating the major glucose transporter gene in Escherichia coli.

@article{Kimata1997cAMPRP,
  title={cAMP receptor protein-cAMP plays a crucial role in glucose-lactose diauxie by activating the major glucose transporter gene in Escherichia coli.},
  author={Keiko Kimata and Hideo Takahashi and Toshifumu Inada and Pieter W. Postma and Hiroji Aiba Aiba},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1997},
  volume={94 24},
  pages={12914-9}
}
The inhibition of beta-galactosidase expression in a medium containing both glucose and lactose is a typical example of the glucose effect in Escherichia coli. We studied the glucose effect in the lacL8UV5 promoter mutant, which is independent of cAMP and cAMP receptor protein (CRP). A strong inhibition of beta-galactosidase expression by glucose and a diauxic growth were observed when the lacL8UV5 cells were grown on a glucose-lactose medium. The addition of isopropyl beta-D-thiogalactoside to… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-4 of 4 references

Kimata et al

S. Ryu, T. M. Ramseier, +5 authors 2489–2496. Biochemistry
Proc. Natl. Acad. Sci. USA 94 • 1997

Escherichia coli and Salmonella tryhimurium

M. L. Saier, Jr., T. M. Ramseier, J. Reizer
Cellular and Molecular Biology, • 1995

Molecular Cloning: A laboratory manual (Cold

J. Sambrook, E. F. Fritsch, T. Maniatis
1989

Experiments in Molecular Genetics. (Cold

J. H. Miller
1972

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