cAMP-dependent regulation of CYP19 gene in rabbit preovulatory granulosa cells and corpus luteum.

Abstract

Transcription of the CYP19 gene encoding the aromatase P450 enzyme in ovarian cells is under the control of the two gonadotropins, follicle stimulating hormone (FSH) and luteinizing hormone (LH), via modulation of intracellular cyclic 3',5'-adenosine monophosphate (cAMP) levels. Primary cultures of rabbit ovarian cells were used to identify the functional… (More)
DOI: 10.1016/j.jsbmb.2009.05.003

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