cAMP and mitochondria.

  title={cAMP and mitochondria.},
  author={Federica Valsecchi and Lavoisier S Ramos-Espiritu and Jochen Buck and Lonny R. Levin and Giovanni Manfredi},
  volume={28 3},
Phosphorylation of mitochondrial proteins has emerged as a major regulatory mechanism for metabolic adaptation. cAMP signaling and PKA phosphorylation of mitochondrial proteins have just started to be investigated, and the presence of cAMP-generating enzymes and PKA inside mitochondria is still controversial. Here, we discuss the role of cAMP in regulating mitochondrial bioenergetics through protein phosphorylation and the evidence for soluble adenylyl cyclase as the source of cAMP inside… CONTINUE READING

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