cAMP/PKA signaling balances respiratory activity with mitochondria dependent apoptosis via transcriptional regulation

@inproceedings{Leadsham2010cAMPPKASB,
  title={cAMP/PKA signaling balances respiratory activity with mitochondria dependent apoptosis via transcriptional regulation},
  author={Jane E Leadsham and Campbell W Gourlay},
  booktitle={BMC Cell Biology},
  year={2010}
}
Appropriate control of mitochondrial function, morphology and biogenesis are crucial determinants of the general health of eukaryotic cells. It is therefore imperative that we understand the mechanisms that co-ordinate mitochondrial function with environmental signaling systems. The regulation of yeast mitochondrial function in response to nutritional change can be modulated by PKA activity. Unregulated PKA activity can lead to the production of mitochondria that are prone to the production of… CONTINUE READING