c-myc oncoprotein in bronchial carcinoma: expression in all major morphological types.

@article{Gosney1990cmycOI,
  title={c-myc oncoprotein in bronchial carcinoma: expression in all major morphological types.},
  author={John R. Gosney and John K. Field and Margot Ann Gosney and Michael Lye and Demetrios A. Spandidos and Shehzad A Butt},
  journal={Anticancer research},
  year={1990},
  volume={10 3},
  pages={623-8}
}
We have studied the prevalence of a 62 kd protein product of the c-myc oncogene in tissue biopsies from 79 primary bronchial carcinomata using the monoclonal antibody Myc 1-9E10 and the avidin-biotin complex (ABC) technique. This oncoprotein was strongly expressed in 43% of 37 squamous lesions, 29% of 14 adenocarcinomata, 42% of 7 non-small cell lesions not further classifiable and 19% of 21 small cell neoplasms, all of classical morphology. There was no statistical difference between groups in… CONTINUE READING
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