c-myc locus amplification and the acquisition of trisomy 8 in the evolution of chronic myeloid leukaemia.

@article{Jennings1998cmycLA,
  title={c-myc locus amplification and the acquisition of trisomy 8 in the evolution of chronic myeloid leukaemia.},
  author={B A Jennings and Ken I. Mills},
  journal={Leukemia research},
  year={1998},
  volume={22 10},
  pages={899-903}
}
The biological progression of chronic myeloid leukaemia is often associated with secondary cytogenetic abnormalities but the molecular mechanisms underlying this progression are poorly understood. This study explores the association of c-myc gene amplification with the progression of chronic myeloid leukaemia in fourteen individuals. Three of these cases showed amplification of c-myc during the course of their disease. Cytogenetic and molecular analysis of serial samples from some patients… CONTINUE READING
19 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 19 extracted citations

Similar Papers

Loading similar papers…