c-Myc enhances protein synthesis and cell size during B lymphocyte development.

@article{Iritani1999cMycEP,
  title={c-Myc enhances protein synthesis and cell size during B lymphocyte development.},
  author={Brian M Iritani and Robert N. Eisenman},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1999},
  volume={96 23},
  pages={13180-5}
}
Members of the myc family of nuclear protooncogenes play roles in cell proliferation, differentiation, and apoptosis. Moreover, inappropriate expression of c-myc genes contributes to the development of many types of cancers, including B cell lymphomas in humans. Although Myc proteins have been shown to function as transcription factors, their immediate effects on the cell have not been well defined. Here we have utilized a murine model of lymphomagenesis (Emu-myc mice) to show that constitutive… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 153 extracted citations

Novel Assay to Detect RNA Polymerase I Activity In Vivo.

Molecular cancer research : MCR • 2017
View 3 Excerpts

References

Publications referenced by this paper.

Selected Methods in Cellular Immunology (Freeman, San Francisco)

R. I. Mishell, S. M. Shiigi
1980

Similar Papers

Loading similar papers…