c-Myc and cancer metabolism.

@article{Miller2012cMycAC,
  title={c-Myc and cancer metabolism.},
  author={Donald M Miller and Shelia D Thomas and A B M Saiful Islam and David E Muench and Kara C. Sedoris},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2012},
  volume={18 20},
  pages={
          5546-53
        }
}
The processes of cellular growth regulation and cellular metabolism are closely interrelated. The c-Myc oncogene is a "master regulator" which controls many aspects of both of these processes. The metabolic changes which occur in transformed cells, many of which are driven by c-Myc overexpression, are necessary to support the increased need for nucleic acids, proteins, and lipids necessary for rapid cellular proliferation. At the same time, c-Myc overexpression results in coordinated changes in… CONTINUE READING

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