c-Kit mutant mouse behavioral phenotype: altered meal patterns and CCK sensitivity but normal daily food intake and body weight.

@article{Chi2003cKitMM,
  title={c-Kit mutant mouse behavioral phenotype: altered meal patterns and CCK sensitivity but normal daily food intake and body weight.},
  author={Michael M. Chi and T L Powley},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2003},
  volume={285 5},
  pages={R1170-83}
}
The mouse W/Wv mutation of the c-Kit receptor causes extensive loss of gastrointestinal interstitial cells of Cajal and vagal intramuscular arrays (IMAs; one of the two putative mechanoreceptors in gastrointestinal smooth muscle). To characterize the behavioral phenotype of the c-Kit mouse and to evaluate the roles of these mechanoreceptors in controlling food intake, meal patterns and daily intakes of W/Wv mice and controls were examined using solid (20-mg pellets) and liquid (Isocal… CONTINUE READING

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A case for interstitial cells of cajal as pacemakers and mediator of neurotransmission in the gastrointestinal tract

  • KM Sanders
  • Gastroenterology 111:
  • 1996
Highly Influential
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