c-Jun enhancement of androgen receptor transactivation is associated with prostate cancer cell proliferation


Androgens and the androgen receptor (AR) are involved in the growth and progression of prostate cancer. Our previous studies suggest that the proto-oncoprotein c-Jun is an AR coactivator that stimulates AR transactivation by mediating receptor dimerization and subsequent DNA binding. To study the physiological relevance of this c-Jun activity on AR, we have… (More)
DOI: 10.1038/sj.onc.1209705


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