c-Fos antisense blocks acquisition and extinction of conditioned taste aversion in mice.

@article{Swank1996cFosAB,
  title={c-Fos antisense blocks acquisition and extinction of conditioned taste aversion in mice.},
  author={Michael W. Swank and Anthony E. Ellis and Bryan N. Cochran},
  journal={Neuroreport},
  year={1996},
  volume={7 11},
  pages={1866-70}
}
Conditioned taste aversion is an unusual form of associative learning in which long delays between conditional stimulus taste (CS) and unconditioned stimulus illness (US) suggest stimulus encoding by novel mechanisms. Recent data suggest that stimulus inputs are encoded by inducible bZIP proteins, the kinetics of which match the temporal features of the CS and US in taste aversion learning. Blockade of US-induced c-Fos translation in the brain stem by antisense oligonucleotides specifically… CONTINUE READING