c-FLIP expression in bladder urothelial carcinomas: its role in resistance to Fas-mediated apoptosis and clinicopathologic correlations.

Abstract

OBJECTIVES To investigate the incidence of Fas (exon 9) mutations and the expression of Fas, Fas-Fas ligand (FasL) system, and cellular FLICE-like inhibitory protein (c-FLIP) in relation to standard clinicopathologic parameters and patient outcome in bladder carcinoma. Disruption of apoptotic cell death has been implicated in tumor aggressiveness in bladder… (More)

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@article{Korkolopoulou2004cFLIPEI, title={c-FLIP expression in bladder urothelial carcinomas: its role in resistance to Fas-mediated apoptosis and clinicopathologic correlations.}, author={Penelope Korkolopoulou and Athina Goudopoulou and Gerassimos E. Voutsinas and Euphemia Thomas-Tsagli and Panagiotis Kapralos and Efstratios S. Patsouris and Angelica A. Saetta}, journal={Urology}, year={2004}, volume={63 6}, pages={1198-204} }