bullwinkle and shark regulate dorsal-appendage morphogenesis in Drosophila oogenesis.

@article{Tran2003bullwinkleAS,
  title={bullwinkle and shark regulate dorsal-appendage morphogenesis in Drosophila oogenesis.},
  author={David H Tran and Celeste A. Berg},
  journal={Development},
  year={2003},
  volume={130 25},
  pages={6273-82}
}
bullwinkle (bwk) regulates embryonic anteroposterior patterning and, through a novel germline-to-soma signal, morphogenesis of the eggshell dorsal appendages. We screened for dominant modifiers of the bullwinkle mooseantler eggshell phenotype and identified shark, which encodes an SH2-domain, ankyrin-repeat tyrosine kinase. At the onset of dorsal-appendage formation, shark is expressed in a punctate pattern in the squamous stretch cells overlying the nurse cells. Confocal microscopy with cell… CONTINUE READING

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