branchless Encodes a Drosophila FGF Homolog That Controls Tracheal Cell Migration and the Pattern of Branching

@article{Sutherland1996branchlessEA,
  title={branchless Encodes a Drosophila FGF Homolog That Controls Tracheal Cell Migration and the Pattern of Branching},
  author={D. Sutherland and C. Samakovlis and M. Krasnow},
  journal={Cell},
  year={1996},
  volume={87},
  pages={1091-1101}
}
  • D. Sutherland, C. Samakovlis, M. Krasnow
  • Published 1996
  • Biology, Medicine
  • Cell
  • The molecular basis for patterning of complex organ structures like the lung and insect tracheal system is unknown. Here, we describe the Drosophila gene branchless (bnl) and demonstrate that it is a key determinant of the tracheal branching pattern. bnl is required for tracheal branching and is expressed dynamically in clusters of cells surrounding the developing tracheal system at each position where a new branch will form and grow out. Localized misexpression of bnl can direct branch… CONTINUE READING

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