binding and silencing activity in healthy mouse liver Disease-linked microRNA-21 exhibits drastically reduced mRNA Material Supplemental

@inproceedings{Androsavich2012bindingAS,
  title={binding and silencing activity in healthy mouse liver Disease-linked microRNA-21 exhibits drastically reduced mRNA Material Supplemental},
  author={John R. Androsavich and B. Nelson Chau and B. Shyamasundara Bhat and Peter S. Linsley and Nils G Walter},
  year={2012}
}
MicroRNAs (miRNAs) bind to mRNAs and fine-tune protein output by affecting mRNA stability and/or translation. miR-21 is a ubiquitous, highly abundant, and stress-responsive miRNA linked to several diseases, including cancer, fibrosis, and inflammation. Although the RNA silencing activity of miR-21 in diseased cells has been well documented, the roles of… CONTINUE READING