beta2-microglobulin serum level is not a marker of disease activity in multiple sclerosis.

@article{Bagnato2004beta2microglobulinSL,
  title={beta2-microglobulin serum level is not a marker of disease activity in multiple sclerosis.},
  author={Francesca R Bagnato and R Zivadinov and D. Cecchinelli and Annalisa Tancredi and Attilio Grop and Alberto Pierallini and C De Lena and Massimiliano Prencipe and Giulio Reale and Marino MD Zorzon and Enrico Millefiorini},
  journal={European journal of neurology},
  year={2004},
  volume={11 7},
  pages={
          455-60
        }
}
Beta2-microglobulin (beta2-MG) is a pharmacodynamic marker of interferon-beta activity in multiple sclerosis (MS). Its role in the natural course of the disease is not fully known. We analyzed the spontaneous fluctuation of beta2-MG in free-treatment MS patients during a short-time course to quantify beta2-MG as a marker of disease activity/progression. Thirty MS patients were clinically assessed and imaged monthly over a 3-month period. Sera were collected concomitantly for the evaluation of… CONTINUE READING