beta2-adrenergic receptor gene polymorphisms in myasthenia gravis (MG).

  title={beta2-adrenergic receptor gene polymorphisms in myasthenia gravis (MG).},
  author={B Y Xu and D Huang and Ritva Pirskanen and Ann Kari Lefvert},
  journal={Clinical and experimental immunology},
  volume={119 1},
The beta2-adrenergic receptor (beta2-AR) belongs to the group of G-protein coupled receptors and is present mainly on skeletal and cardiac muscle cells and lymphocytes. The gene encoding beta2-AR (ADRB2) displays a moderate degree of heterogeneity in the human population. The distribution of polymorphisms at amino acid positions 16, 27 and 164 is changed in asthma, hypertension and obesity. We have earlier reported a decreased density of the beta2-AR on peripheral blood mononuclear cells and… CONTINUE READING