beta subunits influence the biophysical and pharmacological differences between P- and Q-type calcium currents expressed in a mammalian cell line.

Abstract

Human epithelial kidney cells (HEK) were prepared to coexpress alpha1A, alpha2delta with different beta calcium channel subunits and green fluorescence protein. To compare the calcium currents observed in these cells with the native neuronal currents, electrophysiological and pharmacological tools were used conjointly. Whole-cell current recordings of human… (More)

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@article{Moreno1997betaSI, title={beta subunits influence the biophysical and pharmacological differences between P- and Q-type calcium currents expressed in a mammalian cell line.}, author={Herman Moreno and Bernardo Rudy and Rafael H. Llinas}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={1997}, volume={94 25}, pages={14042-7} }