beta-cell neogenesis during prolonged hyperglycemia in rats.

@article{Lipsett2002betacellND,
  title={beta-cell neogenesis during prolonged hyperglycemia in rats.},
  author={M. G. Lipsett and Diane T. Finegood},
  journal={Diabetes},
  year={2002},
  volume={51 6},
  pages={1834-41}
}
beta-cell neogenesis from ductal precursors, and possibly from other pancreatic cell types, contributes to the expansion of beta-cell mass during development and after diabetogenic insults in rodents. Using a mathematical model-based analysis of beta-cell mass, replication, and size, we recently demonstrated that neogenesis is also quantitatively important to the expansion of beta-cell mass during prolonged hyperglycemia. In the present study, we examined the morphological appearance of… CONTINUE READING

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