beta-adrenoceptor blockers as agonists: coupling of beta2-adrenoceptors to multiple G-proteins in the failing human heart.

Abstract

Beta blockers have been shown in clinical trials to improve cardiac function and reduce mortality of heart failure patients. However, these agents require careful titration since they can produce an initial decrease in cardiac output. The authors have recently shown that beta blockers, including some used clinically, can directly depress contraction of… (More)

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Cite this paper

@article{Harding2004betaadrenoceptorBA, title={beta-adrenoceptor blockers as agonists: coupling of beta2-adrenoceptors to multiple G-proteins in the failing human heart.}, author={Sian E Harding and Haibin Gong}, journal={Congestive heart failure}, year={2004}, volume={10 4}, pages={181-5; quiz 186-7} }