beta-Alanine supplementation augments muscle carnosine content and attenuates fatigue during repeated isokinetic contraction bouts in trained sprinters.

  title={beta-Alanine supplementation augments muscle carnosine content and attenuates fatigue during repeated isokinetic contraction bouts in trained sprinters.},
  author={W. Derave and M. Ozdemir and R. Harris and A. Pottier and H. Reyngoudt and K. Koppo and J. A. Wise and E. Achten},
  journal={Journal of applied physiology},
  volume={103 5},
  • W. Derave, M. Ozdemir, +5 authors E. Achten
  • Published 2007
  • Chemistry, Medicine
  • Journal of applied physiology
  • Carnosine (beta-alanyl-l-histidine) is present in high concentrations in human skeletal muscle. The ingestion of beta-alanine, the rate-limiting precursor of carnosine, has been shown to elevate the muscle carnosine content. We aimed to investigate, using proton magnetic resonance spectroscopy (proton MRS), whether oral supplementation with beta-alanine during 4 wk would elevate the calf muscle carnosine content and affect exercise performance in 400-m sprint-trained competitive athletes… CONTINUE READING
    278 Citations

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