beta-Adrenergic control of lipolysis in primate white fat cells: a comparative study with nonprimate mammals.

@article{BousquetMlou1994betaAdrenergicCO,
  title={beta-Adrenergic control of lipolysis in primate white fat cells: a comparative study with nonprimate mammals.},
  author={Alain Bousquet-M{\'e}lou and Jean Galitzky and Christian Carp{\'e}n{\'e} and Max Lafontan and Michel Berlan},
  journal={The American journal of physiology},
  year={1994},
  volume={267 1 Pt 2},
  pages={R115-23}
}
The beta-adrenoceptor subtypes involved in the control of lipolysis in white fat cells of rat, dog, marmoset (Callithrix jacchus), baboon (Papio papio), macaque (Macaca fascicularis), and human were compared. In all species [3H]CGP-12177 binding (up to 3 nM) indicated the existence of a homogeneous population of binding sites in fat cell membranes, and competition studies showed that beta 1- and beta 2-adrenoceptors were present. Selective beta 1 or beta 2-adrenoceptor agonists induced… CONTINUE READING