bantam Encodes a Developmentally Regulated microRNA that Controls Cell Proliferation and Regulates the Proapoptotic Gene hid in Drosophila

@article{Brennecke2003bantamEA,
  title={bantam Encodes a Developmentally Regulated microRNA that Controls Cell Proliferation and Regulates the Proapoptotic Gene hid in Drosophila},
  author={J. Brennecke and David R Hipfner and Alexander Stark and Robert B. Russell and Stephen Michael Cohen},
  journal={Cell},
  year={2003},
  volume={113},
  pages={25-36}
}
Cell proliferation, cell death, and pattern formation are coordinated in animal development. Although many proteins that control cell proliferation and apoptosis have been identified, the means by which these effectors are linked to the patterning machinery remain poorly understood. Here, we report that the bantam gene of Drosophila encodes a 21 nucleotide microRNA that promotes tissue growth. bantam expression is temporally and spatially regulated in response to patterning cues. bantam… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 56 references

2 , E 65 – E 67 . formation

  • D. R. Hipfner, K. Weigmann, S. M. Cohen
  • Bioessays
  • 2002
Highly Influential
7 Excerpts

the c - myc oncogene

  • T. P. Neufeld, A. F. de la Cruz, L. A. Johnston, B. A. Edgar
  • Philos . Trans . R . Soc . Lond . B Biol . Sci…
  • 1998
Highly Influential
4 Excerpts

DNA events . An RNA microcosm

  • A. Bergmann, J. Agapite, K. McCall, H. Steller
  • Science hidUTR Sensor
  • 1998
Highly Influential
4 Excerpts

A new genetic locus controlling growth and proliferation in Drosophila melanogaster

  • P. Léopold
  • Genetics
  • 2003

216 , enzyme dicer in the maturation of the let - 7 small temporal RNA . 671 – 680

  • S. Ortega, M. Malumbres, M. Barbacid
  • Science
  • 2002
1 Excerpt

A characterization detecting tissue specific phenotypes

  • C. Martin-Castellanos, B. A. Edgar
  • Proc . Natl . Acad . Sci .
  • 2002
2 Excerpts

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