Corpus ID: 2106735

aroma.affymetrix: A generic framework in R for analyzing small to very large Affymetrix data sets in bounded memory

@inproceedings{Bengtsson2008aromaaffymetrixAG,
  title={aroma.affymetrix: A generic framework in R for analyzing small to very large Affymetrix data sets in bounded memory},
  author={H. Bengtsson and K. Simpson and James H. Bullard and K. Hansen},
  year={2008}
}
Summary: We have developed a cross-platform open-source framework for analyzing Affymetrix data sets consisting of 1 to 1,000s of arrays. By working directly with CDF and CEL files (standard Affymetrix file formats) most chip types are automatically supported, e.g. expression, SNP, and exon arrays. The package provides methods for low-level analysis such as background correction of different kinds, allelic cross-talk calibration, quantile and affine normalization, PCR fragment-length and GC… Expand
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