araGWAB: Network-based boosting of genome-wide association studies in Arabidopsis thaliana

@inproceedings{Lee2018araGWABNB,
  title={araGWAB: Network-based boosting of genome-wide association studies in Arabidopsis thaliana},
  author={Tak Lee and Insuk Lee},
  booktitle={Scientific Reports},
  year={2018}
}
Genome-wide association studies (GWAS) have been applied for the genetic dissection of complex phenotypes in Arabidopsis thaliana. However, the significantly associated single-nucleotide polymorphisms (SNPs) could not explain all the phenotypic variations. A major reason for missing true phenotype-associated loci is the strict P-value threshold after adjustment for multiple hypothesis tests to reduce false positives. This statistical limitation can be partly overcome by increasing the sample… CONTINUE READING
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