anti(Z-DNA) antibodies in treated patients

Abstract

We studied the effect of hydralazine, an antihypertensive drug with lupus-inducing side effects, on the conformation ofpoly(dGm5dC) poly(dG-m5dC) and a plasmid with a 23 bp insert of (dGdC)" * (dG-dC). sequences. Using an e.l.i.s.a. with a monoclonal anti-(Z-DNA) antibody Z22, we found that hydralazine provoked the Z-DNA conformation in poly(dG-m5dC) -poly… (More)

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Cite this paper

@inproceedings{Thomas2005antiZDNAAI, title={anti(Z-DNA) antibodies in treated patients}, author={Thekkumkattil John Thomas}, year={2005} }