alternative splicing by exon-tiling microarrays MADS : A new and improved method for analysis of differential data

We describe a method, microarray analysis of differential splicing (MADS), for discovery of differential alternative splicing from exon-tiling microarray data. MADS incorporates a series of low-level analysis algorithms motivated by the ‘‘probe-rich’’ design of exon arrays, including background correction, iterative probe selection, and removal of sequence… CONTINUE READING