alphaNAC requires an interaction with c-Jun to exert its transcriptional coactivation.

@article{Qulo2002alphaNACRA,
  title={alphaNAC requires an interaction with c-Jun to exert its transcriptional coactivation.},
  author={Isabelle Qu{\'e}lo and M{\'e}lanie Hurtubise and Ren{\'e} St-Arnaud},
  journal={Gene expression},
  year={2002},
  volume={10 5-6},
  pages={
          255-62
        }
}
alphaNAC is a transcriptional coactivator known to interact with the N-terminal activation domain of the c-Jun transcription factor. In this article, we describe the identification of the c-Jun interaction domain within the alphaNAC protein. Deletion analysis of alphaNAC indicated that the c-Jun binding site was located in the middle part of the protein, between residues 89 and 129. The deletion of the C-terminal end of alphaNAC, including the c-Jun interacting domain, induced a nuclear… CONTINUE READING
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