alpha-Methyl tryptophan as a tracer for in vivo studies of brain serotonin system, from autoradiography to positron emission tomography.

  • Mirko Diksic
  • Published 1992 in Journal of chemical neuroanatomy

Abstract

The procedure for measuring the brain serotonin synthesis rate in living brain using labelled alpha-methyl-L-tryptophan (alpha-MTrp), a tryptophan analog, is described. This tracer could also be used for the anterograde axonal transport measurement of serotonin. One advantage of this method is that alpha-MTrp is converted in situ into a serotonin tracer… (More)

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@article{Diksic1992alphaMethylTA, title={alpha-Methyl tryptophan as a tracer for in vivo studies of brain serotonin system, from autoradiography to positron emission tomography.}, author={Mirko Diksic}, journal={Journal of chemical neuroanatomy}, year={1992}, volume={5 4}, pages={349-54} }