alpha-Lipoic acid and glutathione protect against the prooxidant activity of SOD/catalase mimetic manganese salen derivatives.

Abstract

Manganese(III) N,N'-ethylenebis(salicylideneiminato) chloride (Mn-salen chloride) and manganese(III) N,N'-ethylenebis(3-methoxysalicylideneiminato) chloride (Mn-(3,3'-MeO)salen chloride) are in vitro superoxide dismutase and catalase mimetics. They protect against free radical-related disease in animals, but Mn-salen can also be a potent prooxidant… (More)

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Cite this paper

@article{Fucassi2007alphaLipoicAA, title={alpha-Lipoic acid and glutathione protect against the prooxidant activity of SOD/catalase mimetic manganese salen derivatives.}, author={Flavia Fucassi and Jillian E Lowe and Karl Pavey and Seema K. Shah and Richard G. A. Faragher and Michael H. L. Green and Frank Paul and Danny O'Hare and Peter J. Cragg}, journal={Journal of inorganic biochemistry}, year={2007}, volume={101 2}, pages={225-32} }