alpha-Conotoxins, small peptide probes of nicotinic acetylcholine receptors.

  title={alpha-Conotoxins, small peptide probes of nicotinic acetylcholine receptors.},
  author={R A Myers and G C Zafaralla and William R. Gray and Jordan Abbott and Lourdes J. Cruz and Baldomero M Olivera},
  volume={30 38},
alpha-Conotoxins, a family of small peptides from the venoms of the Conus marine moluscs, are selective, snake alpha-neurotoxin-competitive antagonists of the nicotinic acetylcholine receptor. A new alpha-conotoxin, SIA, has been purified, sequenced, and synthesized. Cross-linking with bivalent reagents and photoaffinity labeling of the acetylcholine… CONTINUE READING