alpha-Conotoxin GI benzoylphenylalanine derivatives. (1)H-NMR structures and photoaffinity labeling of the Torpedo californica nicotinic acetylcholine receptor.

@article{Kasheverov2006alphaConotoxinGB,
  title={alpha-Conotoxin GI benzoylphenylalanine derivatives. (1)H-NMR structures and photoaffinity labeling of the Torpedo californica nicotinic acetylcholine receptor.},
  author={I. E. Kasheverov and David C. Chiara and Maxim N. Zhmak and Innokenty V. Maslennikov and Vladimir S Pashkov and Alexander S. Arseniev and Yuri N Utkin and Jonathan B. Cohen and V. I. Tsetlin},
  journal={The FEBS journal},
  year={2006},
  volume={273 7},
  pages={1373-88}
}
alpha-Conotoxins are small peptides from cone snail venoms that function as nicotinic acetylcholine receptor (nAChR)-competitive antagonists differentiating between nAChR subtypes. Current understanding about the mechanism of these selective interactions is based largely on mutational analyses, which identify amino acids in the toxin and nAChR that determine the energetics of ligand binding. To identify regions of the nAChR involved in alpha-conotoxin binding by use of photoactivated cross… CONTINUE READING